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ACTIVISMADDICTIONAFRICAAGINGAGRICULTUREAIAIDSALGORITHMALIENSANCIENT_WORLDANIMALSANTHROPOLOGYARCHAEOLOGYARCHITECTUREARTASIAASTRONOMYAUDACIOUS_PROJECTAUGMENTED_REALITYAUTISM_SPECTRUM_DISORDERBEAUTYBEHAVIORAL_ECONOMICSBEST_OF_THE_WEBBIODIVERSITYBIOETHICSBIOLOGYBIOTECHBIRDSBLOCKCHAINBOOKSBOTANYBUSINESSCANCERCAPITALISMCHEMISTRYCHINACHRISTIANITYCITIESCLIMATE_CHANGECODECOGNITIVE_SCIENCECOLLABORATIONCOMEDYCOMMUNICATIONCOMMUNITYCOMPASSIONCOMPETITIONCOMPUTERSCONSCIOUSNESSCONSERVATIONCONSUMERISMCORONAVIRUSCORRUPTIONCREATIVITYCRIMECROWDSOURCINGCRYPTOCURRENCYCULTURECURIOSITYCYBER_SECURITYDATADECISION_MAKINGDEMOCRACYDEPRESSIONDESIGNDISABILITYDISEASEDIVERSITYDNADRIVERLESS_CARSDRUGSECOLOGYECONOMICSEDUCATIONEMOTIONSEMPATHYENCRYPTIONENERGYENGINEERINGENTERTAINMENTENTREPRENEURENVIRONMENTEQUALITYETHICSEUROPEEXERCISEEXPLORATIONFAMILYFARMINGFASHIONFEMINISMFILMFINANCEFLIGHTFOODFRIENDSHIPFUNGIFUTUREGAMINGGARDENINGGENDERGENETICSGEOLOGYGLOBAL_ISSUESGOALSGOVERNMENTGRAPHIC_DESIGNHAPPINESSHEALTHHEALTH_CAREHEARTHISTORYHOMELESSNESSHUMAN_BODYHUMAN_RIGHTSHUMANITIESHUMANITYHUMORIDEASIDENTITYILLNESSIMMIGRATIONINCLUSIONINDIAINDUSTRIAL_DESIGNINFRASTRUCTUREINNOVATIONINTERNATIONAL_DEVELOPMENTINTERNATIONAL_RELATIONSINTERNETINTERVIEWINVENTIONINVESTINGJOURNALISMJUSTICE_SYSTEMKIDSLANGUAGELAWLEADERSHIPLGBTQIALIBRARYLIFELITERATURELOVEMACHINE_LEARNINGMAGICMANUFACTURINGMARINE_BIOLOGYMARKETINGMATHMEDIAMEDICAL_RESEARCHMEDICINEMEDITATIONMEMORYMENTAL_HEALTHMIDDLE_EASTMILITARYMONEYMOTIVATIONMUSEUMSMUSICNASANATURAL_DISASTERNATURAL_RESOURCESNATURENEUROLOGYNEUROSCIENCENFTSNUCLEAR_ENERGYOCEANONLINE_PRIVACYPAINPALEONTOLOGYPANDEMICPARENTINGPERSONPERSONAL_GROWTHPERSONALITYPHILOSOPHYPHOTOGRAPHYPHYSICSPLANTSPODCASTPOETRYPOLICYPOLITICSPOLLUTIONPOVERTYPREGNANCYPRODUCT_DESIGNPRODUCTIVITYPROTESTPSYCHOLOGYPUBLIC_HEALTHPUBLIC_SPEAKINGQUANTUMRACEREFUGEESRELATIONSHIPSRELIGIONRENEWABLE_ENERGYROBOTSSCIENCESCIENCE_FICTIONSELFSEXSLAVERYSLEEPSOCIAL_CHANGESOCIAL_MEDIASOCIETYSOCIOLOGYSOFTWARESOUNDSPACESPORTSSTATISTICSSTORYTELLINGSUCCESSSURGERYSUSTAINABILITYSYNTHETIC_BIOLOGYTEACHINGTECHNOLOGYTELEVISIONTERRORISMTHEATERTIMETRANSPORTATIONTRAVELTRUSTUNITED_STATESUX_DESIGNVACCINESVIOLENCEVIRTUAL_REALITYVIRUSVISUALIZATIONSVULNERABILITYWARWATERWEATHERWOMENWOMEN_IN_BUSINESSWORKWORK_LIFE_BALANCEWORK_LIFEWRITINGYOUTH

Results from #CONTACT03

Results from #CONTACT03 are out both @ASCO #ASCO23 and @TheLancet. The 1st phase 3 trial to assess the efficacy of rechallenge with anti-PDL1 in ANY cancer type. According to real world treatment patterns, IO (PD1/L1 inhibitors) rechallenge is common in pts w/ mRCC and other cancer types.

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Toni Choueiri, MD

Senior Executive & Chief GU Cancers @DanaFarber; Prof Medicine @HarvardMed; 2021 Giants of Cancer Award ⚽ lover; 🚲@PanMass, seen on @msnbc @cnn @TODAYshow

mSMART Guidelines for CAR-T Associated Cytokine Release Syndrome

Learn about the mSMART guidelines for the management of CAR-T associated cytokine release syndrome, neurotoxicity, and cytopenias. Find out more about CAR-T associated CRS, neurotoxicity, late neurotoxicity, and post CAR-T cytopenias.

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Vincent Rajkumar

Editor-in-Chief, Blood Cancer Journal; Professor, Mayo Clinic; Opinions are solely my personal views; @CovidThreads; https://t.co/HOGYJSpsoG

Gastric Cancer Risk: The Science Behind the Study

Gastric cancer is a common and often lethal cancer that can be attributed in large part to an infectious cause. In this week's issue of NEJM, Usui et al. provide compelling evidence for a substantial contribution from hereditary forms of gastric cancer. Learn more about the science behind the study here.

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NEJM

The New England Journal of Medicine (https://t.co/YGfDrRsIhE) is the world’s leading medical journal and website.

Misactivation of Developmental Enhancers for the SOX2 Transcription Factor in Breast and Lung Cancer

This paper on @biorxivpreprint explores how misactivation of developmental enhancers for the SOX2 transcription factor leads to overexpression in breast and lung cancer. Learn about the promoter, potential enhancers, and more.

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Michael Hoffman @michaelhoffman@mastodon.social

Computational genomicist, Princess Margaret Cancer Centre. Assoc Prof, Medical Biophysics & Computer Science, University of Toronto. COI https://t.co/CvupKNIjZr